November | 2018 | PhUn Week Blog

Several of the physiologists at the University of Alabama at Birmingham (UAB) have provided considerable time and effort into making PhUn week a great learning experience for K-12 students and teachers in the area. Carmel McNicholas-Bevensee and Kathy Berecek were early PhUn week explorers, taking active learning experiences to the K-5 classrooms in the area, while Mike Wyss conducted both classroom sessions and sessions at the McWane Science Museum in Birmingham. More recently, David and Jennifer Pollock have joined the UAB PhUn week efforts and greatly enhanced its reach.

The original format of UAB PhUn week was to go out to area schools to teach relatively simple, albeit important lessons to K-5 students. Some of the first experiences were to simply take a cow heart to the schools. We quickly realized that the size and weight of a cow heart made the experience difficult, and thus changed to a pig heart-lung preparation, which was more manageable. A plastic tube was inserted into the lungs connected to a bicycle pump, with which the lungs could be expanded with air. For most students this was in itself exciting, but adding to the excitement, the presenter dressed in a white coat and Personal Protective Equipment (PPE) and told the students that as they participated in touch the heart, they too needed to don PPE. We kept the oral presentation short (< 10m), but provided enough background to help the students understand what they were about to experience. Models of the pumping heart, helped the students to gain insight into how blood flows through the pig heart and how the heart worked in them. For middle school students this expanded into 50-minute classroom sessions with human brains, in which the students began to touch the brains and identify major areas.

While many of these experiences were great, one of the most fun experiences is taking the Lung-O-Meter into a grade 2 or 3 classroom. The experience is relatively simple, but teaches several lessons that the teacher can build on. The ingredients are several empty, gallon milk jugs, a plastic tub that has about a > 2-gallon capacity, magic markers, a measuring cup (or graduated cylinder and a flexible plastic tube. The object is to have each team of about 3 students each mark gradations on the milk jug (hopefully in mL), cap the jug when completely filled, turn it upside down, place it in a tub of water remove the cap, place the plastic tube inside the jug, and then blow into the tube to determine lung capacity. The students then put their data points on a graph on the white board in front of the room relative to the student’s weight and height, to estimate whether there is a relationship between these variables. Thus, the lesson teaches them about measurements, scientific process, team work (each student in the group gets an assigned task) and individual differences. Mostly though, it teaches them science can be fun, and what is more fun than 30 7-9 year olds getting to splash around in water in their classroom.

With this or any other similar activity, it is very important to partner with the teacher and administrators in learning experience. Perhaps of prime concern to both groups is that the class time be used to address key learning objectives, typically linked to the Next Generation Science Standards and/or the state’s science course of studies. It is a great benefit for the visitors to explain to the teacher ahead of the visit, the first principles underlying the activity. Grade K-5 teachers often have relatively little formal science background, and thus these PhUn week experiences can be a great learning experience for them as well, as long as they are presented in a collegial way, remembering the visitors can learn much from the teacher about pedagogy of K-5 students. In general, it is best if the PhUn week teams include a faculty-level physiologist, who can help coordinate the activity, but recognizes that the best ideas for the activities likely will come from physiology students/postdocs who design them. Also, the faculty member can often assuage hard feelings when a school cancels an event at the last minute. This will happen and usually relates to emerging situations at the school that are not easily foreseeable.

Just a brief word about mass presentations versus classroom visits. Our presentations at McWane Science Center for both PhUn week and Brain Awareness Week reach a huge number of students in one week (>2,000), especially when they are scheduled for school break periods. However, these events typically do not link up the teachers to the physiologists. Often, once a teacher and physiologist link together in the classroom experience, the teacher is much more likely to engage the physiologist or join in other learning programs that are offered by the physiologist’s institution. Also, the science museum presentations are typically short (2-5 min.) and more focused on the excitement/wonder of science, while the classroom presentations can go more in depth. Over the 10+ years of UAB’s PhUn week, we have reached about >13,000 students in classrooms and >14,000 in the science center.

The engagement of the faculty physiologist also helps researchers address the Broader Impacts that NSF and in part NIH are demanding in applications for research grants. Both granting agencies want to encourage researchers to translate their science to the public, and PhUn week activities can do just that.

	Mike Wyss, Professor of CDIB, Medicine, Neurobiology and Psychology and Director of the Center for Community OutReach Development and the UAB STEM Center received his Ph.D. in Neurobiology from Washington University in St. Louis. In his postdoctoral studies at Washington University School of Medicine under Larry Swanson and Max Cowan, he learned to apply cell biological methods to elucidate the roles of the limbic cortex in behavior and the hypothalamus in autonomic control. He served on the APS Council and is past Chair of the APS Education Committee.
	Kathy Berecek received her Ph.D. from the Department of Physiology and Biophysics at the University of Michigan and subsequently was a postdoctoral scholar at the Universities’ of Michigan, Heidelberg and Iowa. Dr. Berecek is a Professor in CDIB, and a Senior Scientist in the Vascular Biology and Hypertension Program and the Cell Adhesion and Matrix Center. She is also is a Fellow of the AHA, the AHA Hypertension Council, the AHA Council for Atherosclerosis, Thrombosis, and Vascular Biology, and the APS Cardiovascular Section.
	Dr. Carmel McNicholas-Bevensee received both her B.Sc. (Hons) degree (1989) and Ph.D. (1992) from the University of Manchester (England). After completing her postdoctoral training in the Department of Cellular and Molecular Physiology at Yale University in the laboratory of Dr. Gerhard Giebisch, she worked for Bristol-Myers Squibb Pharmaceutical Research Institute and then joined the UAB faculty where she is an Assistant Professor in Cell, Developmental and Integrative Biology (CDIB).

You know you are old when the elementary school part of your K-12 science education would likely disqualify a teacher if he/she tried the approach today. At the start of the week, my 8^th grade teacher wrote about 10 science factoids on the blackboard. On Friday morning, the blackboard was erased and we were given a quiz to see what we “learned” by reading these weekly science tidbits. Science was very boring, although I do recall one funny experience learning about the scientific process. We were asked to interpret some “data,” using inductive reasoning to discern a pattern, make a generalization, and come up with an explanation. We were told the following: “A man drank gin and tonic water and got drunk. He then drank vodka and tonic water and got drunk. And finally he drank rum and tonic water and again he got drunk.” The class enthusiastically and unanimously concluded that tonic water causes you to get drunk.

Despite these beginnings to my science experience, I chose to major in biology in college and learned about physiology thanks to a vertebrate physiology class I took my senior year. On my last day of college, I sat on the floor of the incredible instructor of this course and said, “What can you do with a degree in biology if you don’t want to go to medical school?” He quickly responded, “You seem to really like physiology, so you should get a PhD in physiology.” I blindly followed his advice even though I was clueless what this would entail, but I learned quickly and managed to get accepted into a graduate program where my passion for physiology grew, especially regarding neural control of the cardiovascular system.

The administration of several US Presidents since the late 1950’s has acknowledged that K-12 schools need to do more to educate our population in STEM fields by providing opportunities to ensure that tomorrow’s leaders have the skills needed to be innovative and to maintain a competitive economy. The acronym STEM was popularized in the 1990’s. This is also the era when some national organizations developed opportunities to include exposure to science outside of the classroom and into public arenas. For example, in 1996 The Dana Foundation spearheaded the development of Brain Awareness Week to “to increase public awareness of the progress and benefits of brain research.” It has evolved into a global education initiative with more than 5,600 partners in 120 countries. When I was on the APS Council in 2005, the APS Education Committee promoted an event that would rely on APS members to reach out to their communities to help increase awareness about physiology. This was the beginnings of Physiology Understanding (PhUn) Week, an aptly named event since it was intended to show the public that physiology is fun. We were so lucky that APS Leadership saw a need and was willing to invest a relatively small amount of money (in recent years about $40,000 annually) to stimulate interest in physiology in what has become thousands of young children and hundreds of K-12 teachers each November.

Although I was an early advocate of the program (voting in favor of APS support for the event), my first time to be an active participant in a PhUn Week event was 2009. A teacher at a Jackson MI high school (Nancy Lefere, Lumen Christi High School) contacted APS after reading a notice about the program in a teacher’s magazine. She asked APS how she could find a physiologist who could come to her classroom to participate in PhUn Week, and APS contacted me, and I then reached out to Nancy. I was surprised to learn that she actually teaches a high school physiology course! My colleague Stephanie Watts and I have been going to Lumen Christi High School every year since then. I may be biased, but I think everyone enjoys learning about things that control your blood pressure and heart rate, so we use that as the theme for our PhUn Week activity.

The activity we use at Lumen Christi High School is designed with three goals in mind. One, the students will learn some basic cardiovascular physiology. Two, the students will engage in experimental design. Three, the hands-on activity will educate the students about the cardiovascular effects of drinking caffeinated beverages and aerobic exercise, especially combining the two. Provided one has access to automatic blood pressure and heart rate monitors, the hands-on activity can be done with minimal investment of money (purchase of beverages), and it can be completed in a typical class period.

In the week leading up to the visit by Stephanie and me, Nancy uses the K-W-L- approach to learning as students make lists of things that they Know and Wonder about blood pressure and heart rate. The Learn items are shared with us after our visit to the classroom at the end of the week. Our visit provides students with a valuable opportunity to learn more about blood pressure and heart rate by a Power Point® presentation and the hands-on activity. Some examples of K-W-L items we have gathered over the years are shown in the accompanied K-W-L Chart.

For the hands-on activity, students work in pairs, one being a “researcher” (collects the data) and one is the “subject”. Students receive instructions on the proper way to take their blood pressure using automatic blood pressure cuffs (proper placement of the cuff, arm resting close to heart level, feet flat on floor, relaxed, breathe normally, no talking, etc.). The researchers take and record the blood pressure and heart rate of the subjects on a chart we have prepared in advance. Measurements are made three times: at rest, about 30 minutes after drinking a beverage, and immediately after doing 3-minutes of aerobic exercise (e.g., running, jumping jacks, push-ups). We routinely bring a graduate student with us, giving him/her an opportunity to get engaged in a lively outreach event. And the more hands on deck, the more organized we can be to make sure the students are making the blood pressure and heart arte measurements correctly.

Because the teacher submits the Know and Wonder items in advance of our classroom visit, the presentation can include answers to many of the questions the students posed. The presentation also engages the students by gathering their responses to a variety of questions about blood pressure and heart rate. We used iClicker® technology to gather responses, but if clickers are not available one can do a manual tally of responses to the questions. Typical questions include “Do you know anyone diagnosed with hypertension?”; “Which of the following has the highest blood pressure (or heart rate): a hypertensive man, blue whale, giraffe, or bird?”; “Do you know anyone who had a stroke (or heart attack)?”; “What effect does caffeine (or exercise) have on blood pressure (or heart rate)?”; “Do you think your blood pressure is higher when you are standing, sitting, lying down, or it makes no difference?”

We also talk about the components of experimental design: formulating a hypothesis, developing methods to test a hypothesis, identifying the controls and variables, collecting and recording data, and making a conclusion based on the experimental results. We ask the students what they expect to happen to their blood pressure and heart rate if they consume caffeine and if they exercise. Usually most of the students say that “Drinking caffeinated beverages and exercise will increase my blood pressure and heart rate.”

All students had been asked to refrain from consuming caffeinated beverages for at least 24 hours prior to class. Students are asked in advance if they are sensitive to caffeine and if so, they would not be asked to drink a caffeinated beverage. Parental consent is required to be a subject. Students are divided into groups based on the caffeine-content of the beverage they drink. At a minimum, the study can be done with two beverages: a caffeine-free (0 mg/oz) soft drink and a caffeinated energy drink. We have used either NOS® (10 mg caffeine/oz.) or Rockstar® (15 mg/oz.) energy drink. If possible, all of the beverages used should have the same sugar content so that variation in sugar level is not a factor in the results of the experiment. Also, all students should drink the same volume. It is convenient to use 12-oz as this is the amount in most soft drink cans. The temperature of all of the beverages should also be the same; we use beverages at room temperature.

An almost uniform response is that students who had consumed the energy drink comment that they felt their heart racing after 3-min of exercise. The Figure to the left shows the combined results from our last two visits in which we were able to analyze results from 11 students that drank the caffeinated soft drink and 13 students that drank an energy drink. Systolic pressure (SBP) and heart rate (HR) are both significantly increased after exercise compared to baseline levels in both groups of students. Perhaps surprisingly the results were not significantly greater in those drinking the caffeine-free (CF) beverage versus the caffeinated (C) beverage. One caveat is that blood pressure in these young kids probably begin to correct fairly quickly after they stop exercising. By the time they get back to their seats and settle down to get their pressure and heart rate taken again, it might begin to fall. Students often say they learn not to drink a caffeinated drink before exercising!

In summary, this week-long experience of studying blood pressure and heart rate is a form of active, discovery learning that uses the K-W-L approach in conjunction with a hands-on activity. This format is well-suited to peak the students’ interest in physiology and research because they see for themselves the results of their own study. It mattered more that the students got to be involved in experimental design and conducting the experiments than in the actual results of the experiment. All participants – teachers and students – have PhUn!

The Future of PhUn Week

Many of the APS members who participate in PhUn Week events of other K-12 activities were disheartened to learn that the current APS Council has voted to halt the use of APS funds to support PhUn Week events beginning in 2019. I urge those interested to contact APS Council members to encourage them to reconsider this decision. These events could likely continue with about $20,000 each year. We can bypass the distribution of PhUn Week T-shirts for the APS members and teachers participating in the event and the sports bags given to the students. The trading cards and squeezy hearts could continue to be given as reminders to the kids of the “PhUn” they had on that day in November when a physiologist visited their school. Another option for support of this event is getting dedicated individuals or groups who would be willing to endow the program. Maybe this blog can be used to find APS members willing to help regain support for PhUn Week.

Sue Barman received her PhD in physiology from Loyola University School of Medicine in Maywood, Illinois. Afterward she went to Michigan State University (MSU) where she is currently a Professor in the Department of Pharmacology/Toxicology and the Neuroscience Program. She has had a career-long interest in neural control of cardiorespiratory function with an emphasis on the characterization and origin of the naturally occurring discharges of sympathetic and phrenic nerves. She is also a Fellow of the APS and served as its 85^th President. She has also served as a Councilor of APS and Chair of the Women in Physiology and Section Advisory Committees of the APS. She is active in the Michigan Physiological Society, a chapter of the APS. She established a jeopardy-style Michigan Physiology Quiz in which teams of undergraduate students compete in answering questions about physiology. Students that participate say it is a great way to study for the MCATs. Sue has had a passion for mentoring young physiologists. She is also a recipient of an MSU Outstanding University Woman Faculty Award, a Distinguished Faculty Award, and a Distinguished Service Award from the Association of Chairs of Departments of Physiology.